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1 april 2012 2:19
learning - sharing - connecting
Based in Allan, outside Amman, Jordan, SESAME aims to build scientific expertise in its member countries and bolster cultural ties between them. When completed, the $110-million machine would be the Middle East's only source of high-intensity synchrotron X-rays, which are used in fundamental research ranging from molecular biology to materials science.
The project mirrors the organization of CERN, but Amman is a long way from Geneva — metaphorically as well as literally. In recent years, SESAME has had to contend with the assassination of two members of its Iranian delegation and huge political upheavals in partner countries including Egypt.
Despite the tensions, scientists involved with the project say that SESAME is succeeding because it has something to offer all the participants. Israel, for example, gets a world-class research facility on its doorstep and an opportunity to show its willingness to collaborate with neighbours, says Eliezer Rabinovici, director of the Institute for Advanced Studies at the Hebrew University of Jerusalem, and a member of SESAME's council. Other member states see an opportunity to educate a young and rapidly growing science base. “Turkey is also interested in developing similar laboratories and SESAME would be a very good experience,” says Zehra Sayers, a physicist at Sabancı University in Istanbul and head of SESAME's scientific advisory committee.
Llewellyn Smith is optimistic that the remaining money can be found. Now that local partners have committed funding, the project is more likely to gain support from outsiders such as the United States and the European Union. And other partners in the Middle East, notably Egypt, may yet provide cash, although political turmoil could make commitments difficult.
One of the first steps taken by the collaborations was to form the International Programme on Stem Cell Science and Policy, charged with examining the ethical and religious issues involved in stem-cell science, relevant to Arab culture, and engaging with local communities. Five years on, the plan is bearing fruit.
Hamda Al-Thawadi, Halema Al-Farsi, Heba Al-Siddiqi and Sarah Abdullah joined the Qatar Science Leadership Program (QSLP), a QF initiative that aims to groom Qataris to take leading roles in Qatari science and one day steer its ambitious national programme of research.
The QSLP sends students to train at some of the best universities in the world. And 2011 saw Al-Thwadi and Al-Farsi go to one of France's largest universities, University Paris-Sud 11, Al-Siddiqi go to Harvard Stem Cell Institute in Massachusetts and Abdullah go to the University of Cambridge in the UK.
At the Qatar International Conference on Stem Cell Science and Policy held this past week in Doha, Al-Thawadi, Al-Farsi and Al-Siddiqi presented their research on ovarian cancer and obesity-related diseases. Al-Thawadi practiced medicine for two years before applying for the QSLP. "In the past there was only one path for a medical doctor, treating patients. But when QF started this programme, they created a new path for doctors or graduates interested in science," she says. "This is a perfect chance for Qatar to create home-grown researchers."And Al-Siddiqi is a co-author on a paper published in Nature Cell Biology just this past month:
The first research paper Al-Siddiqi's co-authored was published in Nature Cell Biology in February 2012. "It felt amazing, especially after all the hours of hard work," she says.This is actually pretty neat! Read the full article at Nature Middle East.
Al-Thawadi and Al-Farsi decided to work on ovarian cancer as it is highly prevalent in the Middle East. Al-Thawadi incubated cancer cells in culture with Protein C, a coagulation factor, to test its effect on thrombosis of ovarian cancer cells, which led to a significant increase in metastasis. "This gives us a clue to outline preventative measures for thrombosis in ovarian cancer patients," she explains.
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